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Excreted in breast milkuse cautionAAP states effect on nursing infants is unknown but may be of concern)<\/p>\n

Immediate-release tablets and suspensionInitial dose20 mg orally once a day Maintenance dose20 to 50 mg orally once a day Maximum dose50 mg orally once a day DurationGeneralized Anxiety DisorderEfficacy has been demonstrated for up to 24 weeks in patients responding to treatment during an 8 week treatment phasePosttraumatic Stress DisorderEfficacy has been demonstrated for up to 12 weeksbeing a chronic conditioncontinuation of treatment beyond this time may be considered in responding patients.<\/p>\n

In short-term studiesantidepressants increased the risk of suicidal thinking and behavior in childrenadolescentsand young adultsyounger than 24 yearstaking antidepressants for major depressive disorders and other psychiatric illnesses.<\/p>\n

CommentsImmediate-release oral formulationsThe daily dose may be increased in 10 mg increments at weekly intervalsaccording to clinical response and tolerabilityControlled-release oral formulationsThe daily dose may be increased in 12.5 mg increments at weekly intervalsaccording to clinical response and tolerabilityEfficacy of up to one year was demonstrated with a daily dose averaging 30 mg for the immediate-release formulation and 37.5 mg for the controlled-release formulation.<\/p>\n

CommentsImmediate-release oral formulationsThe daily dose may be increased in 10 mg increments at weekly intervalsaccording to clinical response and tolerabilityControlled-release oral formulationsThe daily dose may be increased in 12.5 mg increments at weekly intervalsaccording to clinical response and tolerabilityEfficacy of up to one year was demonstrated with a daily dose averaging 30 mg for the immediate-release formulation and 37.5 mg for the controlled-release formulation.<\/p>\n

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