In general, therapeutic doses of thiazide diuretics result in a 25 to 40 decrease in lithium clearance with a concomitant increase in serum lithium levels 5 .
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Because lithium is present in cooler, less-massive brown dwarfs, but is destroyed in hotter red dwarf stars, its presence in the stars spectra can be used in the lithium test to differentiate the two, as both are smaller than the sun.
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