In general, therapeutic doses of thiazide diuretics result in a 25 to 40 decrease in lithium clearance with a concomitant increase in serum lithium levels 5 .
Information about Lithium.
SurgeryLithium might change levels of serotonina chemical that affects the central nervous systemThere is some concern that lithium might interfere with surgical procedures that often involve anesthesia and other drugs that affect the central nervous systemLithium use should be stoppedwith the approval of a healthcare providerat least two weeks before a scheduled surgery.
Taking methyldopa might increase the effects and side effects of lithiumDo not take lithium if you are taking methyldopa unless prescribed by your healthcare professional.
TramadolUltramcan affect a chemical in the brain called serotoninLithium can also affect serotoninTaking lithium along with tramadolUltrammight cause too much serotonin in the brain causing confusionshiveringstiff muscles and other side effects.
Lithium might increase how long muscle relaxants workTaking lithium along with muscle relaxants might increase the effects and side effects of muscle relaxantsSome of these muscle relaxants include carisoprodolSomapipecuroniumArduanorphenadrineBanflexDisipalcyclobenzaprinegallamineFlaxedilatracuriumTracriumpancuroniumPavulonsuccinylcholineAnectineand others.
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it is dangerous to continue lithium if you have these side effects.