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Tak this mdication by mouth with without ood as dictd by you docto, usually onc daily. Ask you doctphamacist whn ttak you mdication sinc dint bands a takn at dint tims (ith in th moning, at bdtim). Swallow this mdication whol. Dnot cush, chw, split th capsuls/tablts. Doing scan las all th dug at onc, incasing th isk sid cts.
Th mchanism its antipakinsonic ct is not ully undstood, but it appas tb lasing dopamin om th nv ndings th bain clls, togth with stimulation nopinphin spons. It alshas NMDA cptantagonistic cts. Th antivial mchanism sms tb unlatd. Th dug ints with a vial potin, M2 (an ion channl), which is ndd th vial paticl tbcom “uncoatd” onc it is takn insid th cll by ndocytosis.
Amantadin is availabl as 100 mg tablts capsuls and as a syup containing 50 mg/5ml.
Claanc 0.2 – 0.3 L/h/kg 0.10 +/- 0.04 L/h/kg [halthy, ldly mal] Toxicity.
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